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PfPK6-IN-1

CAT: 0013-GTR19263974-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263974-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PfPK6-IN-1 is a potent and selective inhibitor of PfPK6 with an IC50 value of 0.3 μM. It inhibits the formation of malarial pigment, affecting the unique heme detoxification pathway specific to the parasite, with an IC50 of 13 μM for β-hematin (βH) . PfPK6-IN-1 demonstrates rapid and broad-spectrum antimalarial properties, effective against both sensitive and drug-resistant strains of the parasite. This compound can be utilized in research on antimalarial agents.
CAS Number
2417648-94-1
Field of Research
Infectious Disease & Virology
Smiles
O=C (NC1=NC=CC (OC=2C=CC=3N=C (NC4=CC=C (C (=C4) C (F) (F) F) CN5CCN (CC) CC5) N (C3C2) C) =C1) C6CCN (C) CC6
Molecular Formula
C34H41F3N8O2
Molecular Weight
650.74
Storage Conditions
-20°C
Notes
For research use only.

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