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Nsp12-IN-2

CAT: 0013-GTR19263950-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263950-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nsp12-IN-2 (Compound 8), a triphosphate metabolite of 4'-thiouridine, functions as an inhibitor of SARS-CoV-2 Nsp12. It effectively suppresses the RNA-dependent RNA polymerase (RdRp) activity of the SARS-CoV-2 Nsp12-Nsp7-Nsp8 complex, halting RNA synthesis and blocking the RNA capping and NMP capping of Nsp9. Nsp12-IN-2 shows potential for research into infections caused by SARS-CoV-2, other coronaviruses, and additional RNA viruses.
CAS Number
667882-55-5
Field of Research
Infectious Disease & Virology, Metabolism Research
Smiles
O[C@H]1[C@H] (N2C (NC (C=C2) =O) =O) S[C@@H] ([C@H]1O) COP (OP (OP ([O-]) (O) =O) ([O-]) =O) ([O-]) =O.[Na+].[Na+].[Na+]
Molecular Formula
C9H12N2Na3O14P3S
Molecular Weight
566.15
Storage Conditions
-20°C
Notes
For research use only.

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