EGFR-IN-167

CAT: 0013-GTR19263887-01Size: 10 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19263887-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

EGFR-IN-1671 is a selective EGFR inhibitor with an IC50 value of 0.19 nM. It effectively inhibits various EGFR mutants, showing IC50 values of 0.109 nM for EGFR (L858R), 0.75 nM for EGFR (C797S), and less than 0.05 nM for EGFR (del19) . EGFR-IN-1671 covalently binds to the catalytically conserved lysine of EGFR in live mammalian cells. By inhibiting EGFR autophosphorylation, this compound demonstrates excellent antiproliferative activity. EGFR-IN-1671 is applicable in research on non-small cell lung cancer (NSCLC), glioblastoma, and various solid tumors.

CAS Number

3052761-67-5

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

O=S (=O) (F) OC1=CC=CC (=C1) NC=2N=CN=C3C=C (OCCOC) C (OCCOC) =CC32

Molecular Formula

C20H22FN3O7S

Molecular Weight

467.47

Storage Conditions

-20°C

Notes

For research use only.

Related Products

Catalog	Name
GTR19163234-01	OTS-167
GTR19156368-01	MBQ-167
GTR19174766-01	ML-167
GTR19174276-01	MBQ-167
GTR19189728	ABBV-167
GTR19030311	Jmv 167
GTR19249504-01	JPHM-2-167
GTR17964748	Nhr-167 Antibody
GTR19235662-01	Antibacterial agent 167
GTR19068063-01	Leptin (138-167) (human)

Alternative Products

Catalog	Name
T211515-01	EGFR-IN-167
BA3753-5	MBQ-167
BA3349-5.1	ABBV-167
T9901A-1810-01	AMG-167
T24202	Jmv 167
M11833-01	OTS-167
596370	JWH-167

EGFR-IN-167

Related Products

Alternative Products

Popular Products