Products for Research Use Only

TMPO

CAT: 0013-GTR19263862-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263862-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TMPO (3,3,5,5-Tetramethyl-1-pyrroline 1-oxide) is a spin-trapping agent that targets free radicals. It scavenges superoxide anions and hydroxyl radicals, and inhibits thymocyte apoptosis with an EC50 value of 19.1 mM for DNA fragmentation induced by MPS and 30.7 mM by Etoposide. TMPO reacts with intracellular free radicals to form stable nitroxide radical products, thereby reducing oxidative stress (such as lowering peroxide levels and maintaining glutathione content) and blocking oxidative events in the apoptosis pathway. TMPO shows potential for research in apoptosis of immune cells like thymocytes.
CAS Number
10135-38-3
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
O=N1=CC (C) (C) CC1 (C) C
Molecular Formula
C8H15NO
Molecular Weight
141.21
Storage Conditions
-20°C
Notes
For research use only.

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