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APH02174

CAT: 0013-GTR19263834-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263834-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
APH02174 is a highly selective and orally active IRAK4PROTAC degrader, with a DC50 of 4.01 nM in THP-1 cells. It blocks inflammatory signaling by inhibiting IL-6 release and is applicable for researching inflammatory diseases such as psoriasis and rheumatoid arthritis.
CAS Number
3065494-66-5
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (N1CCC2 (CC=3C (O2) =CC (=C (NC (=O) C=4C=5C (OC4) =CC=CN5) C3) N6CCC (CO) CC6) CC1) [C@H]7CC[C@H] (OCC#CC8=C9C (N (C (=O) N9C) C%10C (=O) NC (=O) CC%10) =CC=C8) CC7
Molecular Formula
C49H55N7O8
Molecular Weight
870.00
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-174455APH02174

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