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MI891

CAT: 0013-GTR19263817-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263817-01Size:10 mg
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Description
MI891 is a highly selective PXR antagonist (IC50= 3.76 μM, Kd= 1.7 μM) and inverse agonist (IC50= 6.1 μM) . It selectively disrupts the interaction between PXR and its coactivator SRC1. MI891 effectively inhibits Rifampicin-induced PXR activation and can be utilized in research on metabolic and other diseases.
CAS Number
2530027-77-9
Field of Research
Metabolism Research
Smiles
O=C (N) C1=CC (=CC=C1Cl) CN2N=NC (=C2) C3=C (N=C4C (F) =CC (F) =CN43) C=5C=CC (Cl) =CC5
Molecular Formula
C23H14Cl2F2N6O
Molecular Weight
499.30
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
HY-175264MI891

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