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IDO1-IN-27

CAT: 0013-GTR19263816-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263816-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IDO1-IN-27 (Compound I-1) is an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO1), displaying an IC50 of 0.3951 μM against recombinant hIDO1. It also inhibits hIDO1 expression in HeLa cells with an EC50 of 62 nM. By reducing the mRNA expression of pro-inflammatory factors (TNF-α, IL-6, and IL-1β), IDO1-IN-27 effectively stimulates T cell proliferation and simultaneously inhibits the growth of LLC cells.
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research
Storage Conditions
-20°C
Notes
For research use only.

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