Products for Research Use Only
RegisterLogin

KBD4466

CAT: 0013-GTR19263773-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19263773-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KBD4466 is a potent oral inhibitor of TLR7 and TLR8, with IC50 values of 0.9 nM and 2.8 nM, respectively. This compound effectively suppresses the inflammatory cytokines IL-6 and IFN-α. KBD4466 has shown to improve disease progression and increase survival rates in the BXSB/MpJ mouse model of systemic lupus erythematosus (SLE) . It is suitable for research into autoimmune diseases.
CAS Number
3023713-87-0
Field of Research
Immunology & Inflammation
Smiles
C (F) (F) (F) [C@@]12[C@@] (C1) (CN (C2) C=3C4=C (C (C#N) =CC3) N=CC=C4) C=5OC (=NN5) C6CCN (C) CC6
Molecular Formula
C24H23F3N6O
Molecular Weight
468.47
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T211376-01KBD4466

Popular Products