Pro-FTY

CAT: 0013-GTR19263727-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19263727-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Pro-FTY is an anticancer prodrug of FTY720 and acts as a sphingosine-1-phosphate (S1P) inhibitor. It specifically inhibits S1P signaling in cancer cells via a drug delivery system (DDS) that reacts with acrolein. pro-FTY significantly reduces the survival of breast cancer cells, including multidrug-resistant cells and organoids resistant to Paclitaxel or Doxorubicin. Additionally, pro-FTY effectively suppresses tumor growth in xenograft mouse models of 4T1 cells or organoids while avoiding lymphopenia.

CAS Number

3064707-13-4

Field of Research

Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Smiles

[N-]=[N+]=NC=1C (=CC (=CC1C (C) C) COC (=O) NC (CO) (CO) CCC2=CC=C (C=C2) CCCCCCCC) C (C) C

Molecular Formula

C33H50N4O4

Molecular Weight

566.77

Storage Conditions

-20°C

Notes

For research use only.

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Catalog	Name
T211329-01	Pro-FTY
C11487-1g	Fingolimod (FTY-720)
BML-SL233-0025	FTY-720 . HCl
HY-114061-01	(R) -FTY 720P
HY-12898	(S) -FTY-720 Vinylphosphonate
463970-01	(R) -FTY-720 Vinylphosphonate
6176/10	FTY 720 10 mg
MBS5813930	(R)-FTY-720 Vinylphosphonate
463969-01	(R) -FTY-720 Phosphonate
1618-25	Fingolimod (FTY-720A, FTY720)

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