RN341

CAT: 0013-GTR19263649-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19263649-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

RN341 is a LRRK2-specific type II kinase inhibitor (IC50 of 296 nM) . It prevents the phosphorylation of LRRK2 by stabilizing an open conformation, thereby avoiding S935 dephosphorylation. Additionally, RN341 rescues LRRK2-mediated kinesin motility blockage by preventing microtubule binding. This compound effectively inhibits both wild-type and G2019S LRRK2 at the cellular level, offering a novel avenue for Parkinson's disease research.

Field of Research

Cell Biology

Storage Conditions

-20°C

Notes

For research use only.

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Alternative Products

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HY-174427	RN341

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