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GPR84 agonist-2

CAT: 0013-GTR19263642-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263642-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GPR84agonist-2 (Compound 8e) is a highly selective GPR84 agonist with an EC50 value of 7.24 nM. It activates the Gαq signaling pathway, leading to the production of inositol triphosphate (IP3) and the release of calcium ions. This compound enhances the chemotaxis of neutrophils and the release of pro-inflammatory cytokines, making it a promising candidate for research into inflammatory diseases such as ulcerative colitis and acute lung injury.
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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