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Topobexin

CAT: 0013-GTR19263628-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263628-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Topobexin (Topobexin 9) is a highly selective TOP2B inhibitor. It selectively inhibits TOP2B in vitro and stabilizes TOP2B on DNA. Topobexin offers significant protection to cardiomyocytes against DAU-induced damage. In rabbit models, Topobexin prevents anthracycline-induced cardiotoxicity and the decrease in left ventricular contractile function caused by DAU.
CAS Number
3076446-44-8
Field of Research
Molecular Biology
Smiles
O=C1OC2=C (C=CC (OCCN3CCN (C) CC3) =C2C (=O) N4C=5C=CC=CC5CCC4) C (=C1) CCC
Molecular Formula
C29H35N3O4
Molecular Weight
489.61
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T211232-01Topobexin

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