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XSJ110

CAT: 0013-GTR19264446-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264446-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XSJ110 is a potent irreversible inhibitor of topoisomerase I (Topo I) with an IC50 value of 0.133 μM. It halts the topoisomerization process of DNA, leading to double-strand breaks and inducing cell cycle arrest in the G0/G1 phase, ultimately causing apoptosis in tumor cells. XSJ110 shows potential for research in ampullary carcinoma (AC) .
CAS Number
203923-65-3
Field of Research
Cell Biology, Molecular Biology
Smiles
C (CC) (=O) C1=C2C (C=3N (C2) C (=O) C4=C (C3) [C@] (CC) (O) C (=O) OC4) =NC=5C1=CC=CC5
Molecular Formula
C23H20N2O5
Molecular Weight
404.42
Storage Conditions
-20°C
Notes
For research use only.

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