Products for Research Use Only

SJL2-1

CAT: 0013-GTR19264146-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264146-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SJL2-1 is a PRMT5 inhibitor with an IC50 value of 1.56 μM. It suppresses the proliferation, migration, and invasion of prostate cancer cells and induces apoptosis while causing cell cycle arrest at the G0/G1 phase. SJL2-1 targets intracellular PRMT5, inhibiting androgen receptor methylation and expression. It is applicable in research on early androgen-sensitive prostate cancer and advanced castration-resistant prostate cancer (CRPC) .
Field of Research
Epigenetics & Chromatin, Metabolism Research
Storage Conditions
-20°C
Notes
For research use only.