Hsp90-IN-42

CAT: 0013-GTR19264002-01Size: 50 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19264002-01Size:50 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Hsp90-IN-42 (Compound 13l) is a potent inhibitor of heat shock protein 90 (Hsp90) with an IC50 of 15.65 nM. It destabilizes the epidermal growth factor receptor (EGFR), inhibits the activation of the EGFR-Akt signaling pathway, induces G0/G1 phase arrest, and slightly triggers apoptosis in colorectal cancer cells, such as HT-29 cells. Additionally, Hsp90-IN-42 suppresses cell proliferation and migration by downregulating CDK12, CDK13, and Bcl-2 protein expression while upregulating Bax protein expression. This compound shows potential for research in colorectal cancer.

Field of Research

Metabolism Research, Signal Transduction

Storage Conditions

-20°C

Notes

For research use only.

Related Products

Catalog	Name
GTR19212443-01	HSP90-IN-18
GTR19186450-01	Hsp90-IN-15
GTR19184789-01	HSP90-IN-10
GTR19184788-01	Hsp90-IN-16
GTR19249959-01	Hsp90-IN-36
GTR19249634-01	Hsp90-IN-39
GTR19240113-01	HSP90-IN-33
GTR19238953-01	HSP90-IN-32
GTR19273385-01	Hsp90β-IN-2
GTR18316802	HSP90 Antibody

Alternative Products

Catalog	Name
T211098-01	Hsp90-IN-42
501825	HSP90
347731-01	HSP90 α
2716-1	AR-42 (HDAC-42)
10R-6731	HSP90 antibody
BA4196-1	HSP90-IN-27
HY-W107935-01	Hsp90-IN-37
T205493-01	Hsp90-IN-38
HY-167827	Hsp90-IN-34
T63827-01	HSP90-IN-10

Hsp90-IN-42

Related Products

Alternative Products

Popular Products