Products for Research Use Only

GJ19

CAT: 0013-GTR19263513-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263513-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GJ19 is a PD-L1 inhibitor with an IC50 of 32.06 nM. It binds effectively to human and mouse PD-L1 proteins, exhibiting KD values of 171 nM and 290 nM, respectively. In a co-culture model of HepG2/hPD-L1 and Jurkat T/hPD-1 cells, GJ19 promotes HepG2 cell death in a concentration-dependent manner. In the B16-F10 melanoma mouse model, GJ19 demonstrates significant tumor growth inhibition. GJ19 is applicable in tumor immunotherapy research.
Field of Research
Cell Biology, Immunology & Inflammation
Storage Conditions
-20°C
Notes
For research use only.

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CatalogName
HY-174830-01GJ19