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Skp2-IN-4

CAT: 0013-GTR19263451-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263451-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Skp2-IN-4 is an Skp2 inhibitor with an IC50 of 0.38 μM for Skp2-Cks1 binding. It enhances antitumor activity by targeting Skp2, inhibiting tumor proliferation, and inducing S phase cell arrest. Skp2-IN-4 also significantly boosts chemosensitivity to Cisplatin in the NCl-H1299 xenograft mouse model by inhibiting tumor cell stemness, presenting potential for lung and esophageal cancer research.
Field of Research
Cell Biology, Protein Biochemistry
Storage Conditions
-20°C
Notes
For research use only.

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