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LRK-4189

CAT: 0013-GTR19263038-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263038-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LRK-4189 is an orally active, selective PIP4K2C PROTAC degrader with a DC50 <500 nM in MOLT-4 cells. It induces endogenous apoptosis and activates the interferon signaling pathway, exhibiting antitumor activity against microsatellite stable (MSS) colorectal cancer (CRC) cells.
CAS Number
3063346-83-5
Field of Research
Pharmacology & Drug Discovery
Purity
99.88% (May vary between batches)
Smiles
FC=1C (C2=CC (=CC=C2) N3C (=O) C=CC=C3) =NC (N[C@@H]4CC[C@@H] (NC (=O) [C@@H]5CC[C@H] (CC5) N6CCN (CC6) C7=C (F) C=C (N[C@@H]8C (=O) NC (=O) CC8) C=C7) CC4) =NC1
Molecular Formula
C43H49F2N9O4
Molecular Weight
793.9
Storage Conditions
-20°C
Notes
For research use only.

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