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BRD4/NAMPT-IN-1

CAT: 0013-GTR19262912-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262912-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BRD4/NAMPT-IN-1 (Compound A2) exhibits strong inhibitory effects on NAMPT and BRD4, with IC50 values of 35 nM (NAMPT) and 58 nM (BRD4) . This compound significantly suppresses the growth and migration of liver cancer cells while promoting apoptosis. Additionally, BRD4/NAMPT-IN-1 demonstrates potent anticancer activity in HCCLM3 xenograft mouse models without noticeable toxicity.
CAS Number
3049218-28-9
Field of Research
Epigenetics & Chromatin, Metabolism Research
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCCCNC (/C=C/C=4C=CC=NC4) =O) =O) N=C2C5=CC=C (Cl) C=C5) =NN=C3C) SC1C
Molecular Formula
C30H30ClN7O2S
Molecular Weight
588.12
Storage Conditions
-20°C
Notes
For research use only.

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