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AT1R antagonist 3

CAT: 0013-GTR19262594-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262594-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AT1R antagonist 3 (Compound 1) is an antagonist of the angiotensin II type 1 receptor (AT1R) and an inhibitor of the L-type calcium channel CaV1.2 (IC50=0.57 μM) . It exhibits vasodilatory effects in isolated rat aorta (10 μM, 88.7%) and shows antihypertensive activity in rat models.
CAS Number
3053482-15-5
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C (O) C=1C=CC=2N=C (SCC=3C=CC (=CC3) C=4C=CC=CC4C5=NN=NN5) NC2C1
Molecular Formula
C22H16N6O2S
Molecular Weight
428.47
Storage Conditions
-20°C
Notes
For research use only.

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