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GT-653

CAT: 0013-GTR19262528-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262528-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GT-653 is a PROTAC degrader targeting lysine-specific demethylase 5B (KDM5B) . It induces the degradation of KDM5B via ubiquitin-proteasome pathways, achieving a degradation rate of 68.35% at a concentration of 10 μM. Additionally, GT-653 upregulates H3K4me3 levels and activates type I interferon signaling pathways in prostate cancer cells 22RV1.
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Molecular Formula
C32H27N7O9
Storage Conditions
-20°C
Notes
For research use only.

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