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PI3Kδ-IN-21

CAT: 0013-GTR19262493-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262493-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PI3Kδ-IN-21 (Compound 31) is a selective inhibitor of phosphoinositide 3-kinase δ (PI3Kδ), with an IC50 of 13.6 nM. It impedes the proliferation and differentiation of T cells through the PI3K/AKT/mTOR signaling pathway. In rat models, PI3Kδ-IN-21 exhibits favorable pharmacokinetic properties and demonstrates activity in improving experimental autoimmune encephalomyelitis induced by myelin oligodendrocyte glycoprotein (MOG) in EAE models.
Field of Research
Signal Transduction
Molecular Formula
C19H16ClN9
Storage Conditions
-20°C
Notes
For research use only.

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