Products for Research Use Only

Anti-inflammatory agent 79

CAT: 0013-GTR19262332-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262332-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-inflammatory agent 79 (compound 17q) is an isoquinolinone derivative-based HIF-1 inhibitor (IC50: 0.55 μM), effectively blocking HIF-1 signaling and promoting the degradation of HIF-1α. It inhibits synovial invasion and migration, as well as angiogenesis. In mouse inflammation models, Anti-inflammatory agent 79 effectively reduces foot swelling and arthritis and lowers levels of inflammatory factors and angiogenesis in vivo.
Field of Research
Epigenetics & Chromatin, Metabolism Research
Molecular Formula
C21H17NO2
Storage Conditions
-20°C
Notes
For research use only.