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Polθ/PARP-IN-1

CAT: 0013-GTR19262029-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262029-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Polθ/PARP-IN-1 (compound 25d) is a potent dual inhibitor of DNA polymerase theta (Polθ) and PARP, with IC50 values of 45.6 nM and 5.4 nM, respectively. This compound exhibits antiproliferative activity, induces apoptosis and cell cycle arrest at the G2/M phase, leading to DNA damage, and demonstrates antitumor properties.
Field of Research
Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Molecular Biology
Molecular Formula
C38H33ClFN7O5S
Storage Conditions
-20°C
Notes
For research use only.

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AN200038PPARP-1/PARP Monoclonal Antibody
MBS5804496PARP-1-IN-1
YP-W34514-01Rat POLγ1 (POLγ1) ELISA Kit
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311204PARP, cleaved (Asp214) (ADP-ribosyltransferase 1, ADPRT, ADPRT1, pADPRT-1, PARP, PARP-1, Poly (ADP-ribose) pol, Poly [ADP-ribose] polymerase 1, Poly[ADP-ribose] synthetase 1, PPOL) discontinued
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BA4382-25PARP-1-IN-4

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