Products for Research Use Only
RegisterLogin

NLRP3-IN-32

CAT: 0013-GTR19262021-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19262021-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NLRP3-IN-32 (compound 7a) is a derivative of 3,4-dihydronaphthalene-1 (2H) -one and acts as an inhibitor of the NLRP3 inflammasome. It obstructs the assembly and activation of the NLRP3 inflammasome by downregulating the expression of NLRP3 and the apoptosis-associated speck-like protein containing a CARD (ASC), thereby reducing the production of reactive oxygen species (ROS) and other inflammatory mediators. Additionally, NLRP3-IN-32 inhibits the phosphorylation of IκBα and NF-κB/p65, as well as the nuclear translocation of p65, thus suppressing NF-κB signaling.
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction
Molecular Formula
C21H22BrN3O
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR18782175-01NLRP3 Antibody
GTR18127034NLRP3 Antibody
GTR18119046-01NLRP3 Antibody
GTR18305151NLRP3 Antibody
GTR17929630-01NLRP3 Antibody
GTR17924103-01NLRP3 Antibody
GTR18590384-01NLRP3 Antibody
GTR19243684-01NLRP3-IN-13
GTR19243206-01NLRP3-IN-71
GTR19238896-01NLRP3-IN-53

Alternative Products

CatalogName
T209380-01NLRP3-IN-32
QY-E06005Human NLRP3 Inflammasome (NLRP3)
MBS8534011-01NLRP3
BA6124-10NLRP3-IN-17
BA6050-10NLRP3-IN-25

Popular Products