Products for Research Use Only

AChE-IN-51

CAT: 0013-GTR19261626-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261626-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AChE-IN-51 (compound 8C) is an orally active, non-competitive inhibitor of AChE and BChE, with IC50 values of 84 nM and 97 nM, respectively. It also inhibits MMP-2 and amyloid β Aβ1-42 aggregation, with IC50 values of 724 nM and 302 nM. Exhibiting low cytotoxicity, AChE-IN-51 is predicted by computational models to penetrate the blood-brain barrier, making it a useful compound for research into diseases such as Alzheimer's disease (AD) .
Field of Research
Neuroscience, Protein Biochemistry, Signal Transduction
Molecular Formula
C23H21OP
Storage Conditions
-20°C
Notes
For research use only.

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