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KRAS G13D-IN-1

CAT: 0013-GTR19261600-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261600-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KRAS G13D-IN-1 (compound 41) is a selective and covalent reversible inhibitor of KRASG13D with an IC50 value of 0.41 nM, exhibiting 29-fold selectivity over wild-type KRAS. It acts as a GDP-state inhibitor and targets the SWII binding pocket of KRASG13D. KRAS G13D-IN-1 inhibits GDP binding to KRAS and modulates downstream signaling cascades.
Field of Research
Signal Transduction
Molecular Formula
C43H45ClF4N8O2
Storage Conditions
-20°C
Notes
For research use only.

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