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(R) -Acenocoumarol

CAT: 0013-GTR19261480-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261480-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -Acenocoumarol ((R) -Acenocoumarin; (R) -Nicoumalone) is a short-acting, orally administered anticoagulant that works by inhibiting vitamin K epoxide reductase (vitamin K1 recycling), similar to Warfarin. It demonstrates greater anticoagulant potency in vivo compared to Warfarin. This compound has a single chiral center, resulting in two enantiomeric forms. The (R) -enantiomer has a longer plasma elimination half-life of 6.6 hours, slower plasma clearance of 1.9 L/h, and stronger anticoagulation effects than the (S) -enantiomer.
CAS Number
66556-77-2
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
CC (C[C@H] (C1=CC=C (C=C1) [N+] ([O-]) =O) C2=C (C3=CC=CC=C3OC2=O) O) =O
Molecular Formula
C19H15NO6
Molecular Weight
353.33
Storage Conditions
-20°C
Notes
For research use only.

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