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Thalidomide 4'-ether-PEG2-azide

CAT: 0013-GTR19261448Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19261448Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thalidomide 4'-ether-PEG2-azide is a modified form of the cereblon (CRBN) inhibitor Thalidomide, created through click chemistry. Featuring an azide group, this compound can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. It serves as a ligand for E3 ubiquitin ligase and as a linker conjugate (E3LigaseLigand-Linker Conjugates) for use in PROTACs.
CAS Number
2758431-90-0
Field of Research
Metabolism Research; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery
Smiles
[N-]=[N+]=NCCOCCOCCOC1=CC=CC=2C (=O) N (C (=O) C12) C3C (=O) NC (=O) CC3
Molecular Formula
C19H21N5O7
Molecular Weight
431.40
Storage Conditions
-20°C
Notes
For research use only.

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