IGUANA-1

• Description :

  IGUANA-1 is a potent and selective ALDH1B1 inhibitor. IGUANA-1 shows no significant mitochondrial toxicity. IGUANA-1 has antitumor activity[1].

• UNSPSC :

  12352005

• Target :

  Aldehyde Dehydrogenase (ALDH)

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/iguana-1.html

• Purity :

  98.93

• Solubility :

  DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=CO.COC1=CC(Cl)=CC=C1C(N2C3=NCCC2)=CN3C(C=C4)=CC=C4C5=CC=CC=C5OC

• Molecular Formula :

  C27H26ClN3O4

• Molecular Weight :

  491.97

• References & Citations :

  [1]Feng Z, et al. Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1. Nat Chem Biol. 2022 Oct;18 (10) :1065-1075.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  ALDH1

• CAS Number :

  [2756014-25-0]