IGUANA-1

• UNSPSC Description:

  IGUANA-1 is a potent and selective ALDH1B1 inhibitor. IGUANA-1 shows no significant mitochondrial toxicity. IGUANA-1 has antitumor activity[1].

• Target Antigen:

  Aldehyde Dehydrogenase (ALDH)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/iguana-1.html

• Solubility:

  DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=CO.COC1=CC(Cl)=CC=C1C(N2C3=NCCC2)=CN3C(C=C4)=CC=C4C5=CC=CC=C5OC

• Molecular Weight:

  491.97

• References & Citations:

  [1]Feng Z, et al. Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1. Nat Chem Biol. 2022 Oct;18(10):1065-1075.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported

• CAS Number:

  2756014-25-0