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MLK-IN-1

CAT: 0013-GTR19264862-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264862-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MLK-IN-1 is a potent and selective mixed-lineage kinase 3 (MLK-3) inhibitor, showing excellent brain penetration and high specificity for MLK-3. MLK-IN-1 at 100 nM supports sustained axonogenesis in cultures challenged with HIV-1 Tat-activated microglia and protects neuronal cells from Tat-induced damage, establishing it as a valuable probe for neuroinflammation and neurodegeneration research.
CAS Number
1627729-62-7
Field of Research
Signal Transduction
Purity
99.74% (May vary between batches)
Smiles
N=1C=C (C=2SC=3C (OC) =CC=CC3C2) N4N=C (C=CC14) NC5=CC=C (OC) C (OC) =C5
Molecular Formula
C23H20N4O3S
Molecular Weight
432.5
Storage Conditions
-20°C
Notes
For research use only.

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BA6508-10MLK-IN-1
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323103MAP3K11 (Mitogen-activated protein kinase kinase kinase 11, MLK3, PTK1, SPRK, MLK-3, MEKK11) discontinued
500273MLK3, Recombinant, Human, GST-Tag (Mixed-Lineage Kinase 3, MAP3K11, PTK1, SPRK, MLK3, MGC17114, MLK-3) discontinued
223975-01LZK (Mitogen-Activated Protein Kinase Kinase Kinase 13, Leucine Zipper-bearing Kinase, Mixed lineage Kinase, MLK, MAP3K13, LZK) discontinued
135497-FITCMLTK (Mitogen-activated Protein Kinase Kinase Kinase MLT, Human Cervical Cancer Suppressor Gene 4 Protein, HCCS4, HCCS-4, Leucine Zipper- and Sterile alpha Motif-containing Kinase, MLK-like Mitogen-activated Protein Triple Kinase, Mixed Lineage Kinase-related Kinase, MLK-related Kinase, MRK, Sterile alpha Motif- and Leucine Zipper-containing Kinase AZK, ZAK) (FITC)
135497-APCMLTK (Mitogen-activated Protein Kinase Kinase Kinase MLT, Human Cervical Cancer Suppressor Gene 4 Protein, HCCS4, HCCS-4, Leucine Zipper- and Sterile alpha Motif-containing Kinase, MLK-like Mitogen-activated Protein Triple Kinase, Mixed Lineage Kinase-related Kinase, MLK-related Kinase, MRK, Sterile alpha Motif- and Leucine Zipper-containing Kinase AZK, ZAK) (APC)

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