Products for Research Use Only

BIEGi-1

CAT: 0013-GTR19264764-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264764-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BIEGi-1 is a potent and selective EGFR dimerization inhibitor that effectively blocks EGFR-catalyzed nucleotide exchange and disrupts the EGFR-Rheb interaction. It strongly inhibits EGFR kinase activity and mTORC1 signaling in EGFR-mutant cancer cells. BIEGi-1 exhibits significant antiproliferative effects, with an IC50 of 17 nM against [PC9] and an IC50 of 20 nM against [HCC827].
Storage Conditions
-20°C
Notes
For research use only.