BIEGi-1

CAT: 0931-T212579-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T212579-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Others

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Bioactivity

BIEGi-1 is a potent and selective EGFR dimerization inhibitor that effectively blocks EGFR-catalyzed nucleotide exchange and disrupts the EGFR-Rheb interaction. It strongly inhibits EGFR kinase activity and mTORC1 signaling in EGFR-mutant cancer cells. BIEGi-1 exhibits significant antiproliferative effects, with an IC50 of 17 nM against [PC9] and an IC50 of 20 nM against [HCC827].

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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E6000-25mg	BIEGi-1
OF59775-01	1,1,1,1,1-Kestoheptaose
N2864-5.1	1,1,1,1-Kestohexaose
112040	1,1,1,1-Kestohexose

BIEGi-1

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