Products for Research Use Only
RegisterLogin

Recombinant Human Bone Morphogenetic Protein 7

CAT: 0355-AP60122Size: InquireDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0355-AP60122Size:Inquire
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Bone Morphogenetic Protein 7 is one of the BMPs, some of which belong to the TGF-beta superfamily (BMP2-7) . There are more than thirteen BMPs have been discovered nowadays and they are involved in inducing cartilage and bone formation. BMP-7 is mainly expressed in kidney and bladder. It is also present in developing eyes, brain and ear during embryogenesis. BMP-7 also named osteogenic protein-1 (OP-1) is a potent osteoinductive cytokine and plays role in osteoblast differentiation, SMAD1 production and renal development and repair. Human BMP-7 is synthesized with a signal sequence (29 a.a.), a propeptide (263 a.a.), and a growth factor domain (139 a.a.) . The growth factor domain of human BMP-7 shares 98 % a.a. sequence identity with mouse and rat BMP-7.
Product Name Alternative
OP-1
Gene ID
655
UniProt
P18075
Target
STGSKQRSQN RSKTPKNQEA LRMANVAENS SSDQRQACKK HELYVSFRDL GWQDWIIAPE GYAAYYCEGE CAFPLNSYMN ATNHAIVQTL VHFINPETVP KPCCAPTQLN AISVLYFDDS SNVILKKYRN MVVRACGCH
Purification
> 95 % by SDS-PAGE and HPLC analyses.
Endotoxin
Less than 1 EU/ug of rHuBMP-7 as determined by LAL method.
Bioactivity
Data is not available.
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculated Molecular Weight
Approximately 15.7 kDa, a monomeric, non-glycosylated polypeptide chain containing 139 amino acids.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in 30 % acetonitrile, 0.1 % TFA.
Host or Source
Escherichia coli

UniProtKB · P18075

Bone morphogenetic protein 7

BMP7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P18075
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BMP7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
BMP-7
EC number
—
Processing
Precursor
Secondary accessions
Q9H512, Q9NTQ7
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Biological process

ChondrogenesisDifferentiationOsteogenesis

Molecular function

CytokineDevelopmental proteinGrowth factor

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

Related Products

CatalogName
AP78665-01Bone morphogenetic protein 7
AP81034Bone morphogenetic protein 7
AP81209Bone morphogenetic protein 7
EK2258Human Bone morphogenetic protein 7 ELISA Kit
42441Bone morphogenetic protein 7 Polyclonal Antibody
AP60121Recombinant Human Bone Morphogenetic Protein 3
AP60127Recombinant Human Growth Differentiation Factor 7/Bone Morphogenetic Protein-12
C42441Bone morphogenetic protein 7 Polyclonal Conjugated Antibody
AP70085-01Recombinant Human Bone morphogenetic protein 3(BMP3)
AP70084-01Recombinant Human Bone morphogenetic protein 1(BMP1)

Alternative Products

CatalogName
476286BMP5 (Bone Morphogenetic Protein 5 (Predicted), Bone Morphogenetic Protein 5)
308107Bone morphogenetic Protein 7
545484Bone Morphogenetic Protein 8B
545462Bone Morphogenetic Protein 4
545454Bone Morphogenetic Protein 2
GTR19019423-01Bone morphogenetic protein 15
GTR19019279-01Bone morphogenetic protein 1
GTR19018946-01Bone morphogenetic protein 10
GTR19018782-01Bone morphogenetic protein 6
GTR19018621-01Bone morphogenetic protein 5

Popular Products