KWZY-11

CAT: 0013-GTR19263661-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19263661-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

KWZY-11 (Compound 11) is a potent dual inhibitor of PARP/CDK6, exhibiting IC50 values of 156.8 nM, 197.3 nM, and 13.3 nM for PARP1, PARP2, and CDK6 respectively. It suppresses tumor cell proliferation by modulating the Wnt/β-catenin signaling pathway. Additionally, KWZY-11 induces excessive DNA damage and apoptosis in MDA-MB-231 breast cancer cells.

Field of Research

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction, Stem Cell & Developmental Biology

Storage Conditions

-20°C

Notes

For research use only.

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T211261-01	KWZY-11
BA7082-1	11β-HSD1-IN-11
BUP12606-01	11ß-HSD1-IN-11
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B688439	1-Bromoundecane-11,11,11-d3
053198	11-OHP (11-Hydroxyprogesterone)
T8782-01	MitoBloCK-11 (MB-11)
GWB-867D56	Interleukin-11 (IL-11)
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KWZY-11

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