ML-20

CAT: 0013-GTR19263702-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19263702-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

ML-20, an analog of Malabaricone C, functions as both an autophagy inhibitor and a radiosensitizer. It suppresses cell proliferation and induces apoptosis (cell death) . ML-20 also causes DNA double-strand breaks, loss of mitochondrial membrane potential (MMP), and lysosomal membrane permeabilization (LMP) . Due to LMP, it triggers endoplasmic reticulum stress while concurrently inhibiting autophagic flux.

Field of Research

Cell Biology

Storage Conditions

-20°C

Notes

For research use only.

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