Products for Research Use Only

IRAK1-IN-1

CAT: 0013-GTR19262648-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262648-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IRAK1-IN-1 (compound B8) is an orally active IRAK1 inhibitor. It suppresses IL-6 release in murine J774A cells and human THP-1 cells, with IC50 values of 4.57 μM and 6.51 μM, respectively. Additionally, IRAK1-IN-1 alleviates LPS-induced acute lung injury and DSS-induced colitis in mice.
Field of Research
Immunology & Inflammation, Signal Transduction
Molecular Formula
C17H20N2O4
Storage Conditions
-20°C
Notes
For research use only.