QC-182

CAT: 0013-GTR19261784-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19261784-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

QC-182 is a potent p300/CBP PROTAC degrader. It reduces p300 protein levels in SK-HEP-1 cells with a DC50 of 93 nM. QC-182 effectively inhibits cell growth in SK-HEP-1 and JHH7 cell lines, with IC50 values of 0.733 μM and 0.477 μM, respectively. QC-182 is applicable for hepatocellular carcinoma (HCC) research.

CAS Number

3032646-96-8

Field of Research

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Smiles

O=C1N ([C@H] (C=2N (C=3C (N2) =CC (=CC3) C=4C (C) =NOC4C) C5CCN (CC5) C6CN (C6) C=7C=C8C (=CC7) C (=O) N (C8=O) C9C (=O) NC (=O) CC9) CCC1) C%10=CC (F) =C (F) C=C%10

Molecular Formula

C44H42F2N8O6

Molecular Weight

816.85

Storage Conditions

-20°C

Notes

For research use only.

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