Products for Research Use Only

LPPM-8

CAT: 0013-GTR19262165-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262165-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LPPM-8 is a ligand for Med25 and acts as an inhibitor of Med25 protein-protein interactions (PPI) . It engages with Med25 via the H2 surface of its activator-interaction domain, thereby stabilizing full-length proteins in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcription activators (e.g., ATF6a) . Med25 plays a role in the transcriptional regulation of RNA polymerase II-dependent genes and can form a transcription complex with ATF6α. LPPM-8 is valuable for studying the complex biology of Med25 and its Mediator complex.
Molecular Formula
C50H89N7O14
Storage Conditions
-20°C
Notes
For research use only.

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