Dac590

CAT: 0013-GTR19260135-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19260135-01Size:100 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Dac590 is an orally active FTO inhibitor. Dac590 has a robust antiproliferative effect on AML cells, and induces apoptosis and cell cycle G1 arrest by inhibiting oncogenic FTO signaling. Dac590 significantly inhibits tumor growth and prolongs survival with no observed toxicity in acute myeloid leukemia (AML) xenograft mcie model, and shows a synergistic effect combined with Decitabine (HY-A0004) .

CAS Number

3084407-00-8

Purity

>98%

Smiles

OC (C1=CC (OC) =CC=C1NC2=C (C=C (C=C2Cl) C3=C (ON=C3C) C) F) =O

Molecular Formula

C19H16ClFN2O4

Molecular Weight

390.79

Notes

For research use only.