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Lipid 88

CAT: 0013-GTR19259757-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19259757-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Lipid88​​ is a high-performance, novel ionizable lipid component engineered for advanced mRNA-LNP vaccine delivery. LNP88 formulation demonstrates superior biodistribution, achieving >10-fold higher transfection efficiency in spleen and lymph nodes compared to benchmark lipids like ALC-0315 via intramuscular delivery. When encapsulating antigen-encoding mRNA (e.g., optimized mCSA construct), Lipid-88 based LNPs drive robust humoral and cellular immunity, enabling complete protection against challenging SARS-CoV-2 variants (WA1/2020, Omicron BA.1, BQ.1) in preclinical models. Its design prioritizes potent immunogenicity with favorable safety profiles.
CAS Number
2982842-99-7
Field of Research
Metabolism Research
Purity
>98%
Smiles
CCCCCCC (CCCC) COC (OCCOC (CCN (CCC (OCCOC (OCC (CCCC) CCCCCC) =O) =O) CCCN (C) CCCN (CCC (OCCOC (OCC (CCCC) CCCCCC) =O) =O) CCC (OCCOC (OCC (CCCC) CCCCCC) =O) =O) =O) =O
Molecular Formula
C79H147N3O20
Molecular Weight
1459
Notes
For research use only.

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