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Yck2-IN-1

CAT: 0013-GTR19258806-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258806-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 μM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.
CAS Number
401816-26-0
Field of Research
Infectious Disease & Virology, Metabolism Research, Stem Cell & Developmental Biology
Smiles
N#CC=1C=CC2=C (C=3C=CN=CC3) C (=NN2C1) C=4C=CC (F) =CC4
Molecular Formula
C19H11FN4
Molecular Weight
314.316
Storage Conditions
-20°C
Notes
For research use only.

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