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PUC-10

CAT: 0013-GTR19259246-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19259246-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PUC-10 is a 5-HT6 receptor antagonist with a Ki of 14.6 nM and an IC50 of 32 nM. Computer simulations suggest that PUC-10 is orally active and capable of crossing the blood-brain barrier. It induces autophagy in SH-SY5Y cells by inhibiting the mTOR pathway. PUC-10 is applicable in the study of neurological disorders.
CAS Number
2095549-31-6
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Smiles
S (=O) (=O) (N1C=2C (C ([C@@H] (CN3CCN (CC3) C4=C (OC) C=CC=C4) O) =C1) =CC=CC2) C=5C6=C (C=CC5) C=CC=C6
Molecular Formula
C31H31N3O4S
Molecular Weight
541.661
Storage Conditions
-20°C
Notes
For research use only.

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