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Akt1-IN-8

CAT: 0013-GTR19259146-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19259146-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Akt1-IN-8 (Compound JL18) is a potent AKT1 kinase inhibitor with oral bioavailability of 41% and an IC50 value of 8.8 nM. It exhibits significant antiproliferative effects against PC-3 prostate cancer cells, with an IC50 of 3.0 μM. Akt1-IN-8 also reduces phosphorylated GSK3β levels.
CAS Number
2247688-87-3
Field of Research
Signal Transduction
Smiles
O=C (N1CCN (C=2N=CN=C3NN=C (Br) C32) CC1) C (C4=CC=C (Br) C=C4) CNC (C) C
Molecular Formula
C21H25Br2N7O
Molecular Weight
551.278
Storage Conditions
-20°C
Notes
For research use only.

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