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TEC 4

CAT: 0013-GTR19258424-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258424-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TEC 4 is a ByeTAC (bypass E3 ligase targeting chimera) that acts as a BRD4 degrader. At a concentration of 500 nM, it results in 33% residual BRD4 in Ramos B cells. Additionally, TEC 4 exhibits toxicity in Ramos B cells with an IC50 of 30.5 nM. ByeTAC recruits proteins directly to the proteasome for degradation by interacting with Rpn-13.
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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