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NLRP3-IN-76

CAT: 0013-GTR19258364-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258364-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NLRP3-IN-76 is an orally active NLRP3 inhibitor that suppresses the production of NO and reduces the mRNA levels of pro-inflammatory cytokines (iNOS, IL-6, IL-1β, and TNFα) . It exerts anti-inflammatory effects by inhibiting the activation of the NLRP3 inflammasome and the NF-κB signaling pathway. Furthermore, NLRP3-IN-76 can ameliorate DSS-induced colitis and is applicable for studying inflammatory bowel disease (IBD) .
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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