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ABZI

CAT: 0013-GTR19257981-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257981-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -2- (1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido) -1- (2-hydroxy-2-phenylethyl) -1H-benzo[d]imidazole-5-carboxamide (compound 4) is a STING agonist containing the crucial amide benzimidazole (ABZI) component. It consistently inhibits the binding of 3 H-cGAMP to STING, with an apparent inhibition constant (IC50) of 14 μM. This compound is applicable in tumor research.
CAS Number
2248444-14-4
Field of Research
Immunology & Inflammation
Smiles
C ([C@@H] (O) C1=CC=CC=C1) N2C=3C (N=C2NC (=O) C=4N (CC) N=C (C) C4) =CC (C (N) =O) =CC3
Molecular Formula
C23H24N6O3
Molecular Weight
432.48
Storage Conditions
-20°C
Notes
For research use only.

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