FLY26

CAT: 0013-GTR19257969-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19257969-01Size:10 mg

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Description

FLY26 is a selective partial antagonist of GluN2B, with an IC50 value of 0.64 μM. FLY26 inhibits the GluN2B subunit of NMDA receptors, reducing calcium ion influx and reactive oxygen species (ROS) production. It also activates the BDNF/TrkB/CREB neuroprotective signaling pathway, mitigating excitotoxicity and mitochondrial dysfunction. FLY26 holds potential for treating neurological deficits caused by cerebral ischemia-reperfusion injury.

Field of Research

Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C22H23N5O3

Storage Conditions

-20°C

Notes

For research use only.

Alternative Products

Catalog	Name
HY-172876	FLY26

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