Amyloid-β-IN-3

CAT: 0013-GTR19257941-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19257941-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Amyloid-β-IN-3 (EX.113) is a selective inhibitor of γ-secretase. It demonstrates inhibitory activity on Aβ42 secretion in H4 cells, with an EC50 value of 148 nM. By modulating the catalytic activity of γ-secretase, Amyloid-β-IN-3 decreases Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. It holds potential for Alzheimer's disease (AD) research.

CAS Number

1603833-56-2

Field of Research

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Smiles

C (NC1=CC (F) =CC (F) =C1) (=O) C2=CC=3C (N2) =CC=C (C3) [C@H]4CN (C (C) =O) CCC4

Molecular Formula

C22H21F2N3O2

Molecular Weight

397.42

Storage Conditions

-20°C

Notes

For research use only.

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Amyloid-β-IN-3

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